Lancet. 2016 Jun 25;387(10038):2614-2621.
Hysteroscopy is an invasive procedure for diagnosis and treatment of abnormal findings in the endometrial cavity recognized by detailed transvaginal U/S. However hysteroscopy has been also widely suggested by infertility specialists for women with normal U/S before or after failed IVF cycle as a step to increase success in IVF. Two well-conducted, multicenter, randomized controlled trials, “inSIGHT” and “TROPHY”, have been published in Lancet addressing this IVF add-on.
Both studies revealed that routine hysteroscopy before and after an IVF failure suggested for women with normal endometrial cavity as observed by transvaginal U/S, does NOT improve live birth rates. Since hysteroscopy is an invasive and relative expensive procedure such an approach must be properly and extensively justifiable.