N Engl J Med. 2019 Jan 24;380(4):325-334.
Endometrial scratching (ES) is an IVF adds-on procedure widely adopted by infertility specialists claiming improvement of IVF results. Lensen S et al. published in NEJM a well conducted, multicenter, randomized controlled trial addressing the role of endometrial scratching in IVF. The study had the power to detect a between group differences in live births about a reasonable 7%. They concluded that ES before IVF has no effect on live birth rates. Therefore, offering ES before IVF and charging patients for it is very questionable.